June 17, 2020
Today’s yFile showcased the recent published work by Dr. Kashif Aziz Khan (Research Associate) and Prof. Peter Cheung. Their study looked at the primer/probe targets of over 17,000 viral SARS-CoV2 (COVID-19) sequences used in PCR (polymerase chain reaction) diagnostic assays. They found 7 out of 27 published PCR assays had mismatches or mutations in the targeted sequences. Their findings suggest periodic re-evaluation of PCR assays used for diagnosing COVID-19 should be implemented to ensure accuracy and confidence in the tests. Dr. Khan’s and Prof. Cheung’s paper is published in Royal Society Open Science: Khan and Cheung, Royal Society 2020.